Prof. Michal Lotem, MD

Head Of The Hadassah Cancer Research Institute

The founder and Head of the Hadassah Cancer Research Institute, Professor Michal Lotem is an international expert in skin cancer and clinical oncology, driving cutting-edge scientific innovation at the HCRI since its inception in 2019. Her vision for HCRI is to investigate the nature of various cancers and enable HRCI’s physicians, scientists and researchers to develop new and personalized ways to manipulate the immune system to cure cancer, with the goal of eradicating cancer.

  • Michal’s research interests aim to immunize patients against cancer by discovering novel adoptive cell therapies, as well as the development of immunotherapies for malignant melanoma. In her lab [Cancer Immunotherapy], Prof. Lotem and her research team are working toward developing anti-cancer therapies that harness the body’s own immune system via an approach that combines innovative basic research with a personalized treatment protocol that only a handful of global oncology centers can offer.
  • In addition to managing the HCRI, Prof. Lotem is the Head of the Center for Melanoma and Cancer Immunotherapy at Hadassah Medical Center, leads  CancerRNA, a global science research consortium that aims to apply RNA-based therapeutics to successfully unlock anti-cancer immune responses, and lectures on Clinical and Radiation Oncology at Hadassah Hebrew University Hospital.
  • The recipient of numerous global grants for cancer research projects, Prof. Lotem serves as a scientific advisor to several startups developing novel cancer therapies. She is also currently a partner in the Horizon 2020 Marie Skłodowska-Curie Actions, researching  ITN T-OP Training Network for Optimizing Adoptive T cell Therapy of Cancer. In addition to her academic experience in Israel, Michal has been a visiting Professor at Stanford University’s Division of Oncology and a visiting scholar at the MIT’s Broad Institute.
  • Prof. Lotem received her MD from Tel Aviv University’s Sackler School of Medicine, and did residencies in the Department of Dermatology and the Department of Oncology at Beilinson Medical Center. After completing her residency in oncology, she joined the Department of Dermatology at Hadassah University Hospital. During her service in the Israel Defense Forces, Michal served as a Flight Surgeon and the  Commander of Medical Services at an Air Force base.
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